Case Studies

Johnson Matthey Pharma Services has helped thousands of companies realize their next development milestone by drawing on our vast experience. From medicinal chemistry programs to commercial API production we have overcome numerous challenges that allow our customers to maintain their timelines. Our ability to combine specialty capabilities such as catalyst technology, separations and high potency synthesis also brings an added advantage to deliver your program’s needs.

Read through some examples of how Johnson Matthey has successfully delivered when it counts:

Case Studies

Utilizing Johnson Matthey catalyst technology to manufacture a difficult-to-source starting material (98.92 KB)
A complex starting material for a kg-scale GMP synthesis was prohibitively expensive and hard to source. An alternative route employing catalytic carbonylation was developed and performed on multi-kg scale to supply material.

Production of a commercially approved API (99.31 KB)
Process validation and commercial production of a complex multi-step potent API with Big Pharma client.

Development of a scalable process from a g-scale medicinal chemistry route (36.7 KB)
Client needed JMPS to develop an economical, scalable process from the original medicinal chemistry route (gm) for plant production (100+ kg).

Process Research and Development for a Scalable Synthesis of a Natural Product API (98.33 KB)
Pharma Division of a large corporation desired a scalable kg synthesis of a complex natural product for pre-clinical studies.

5-Year Medicinal Chemistry client program ending in acquisition by large Pharma company (36.29 KB)
Local client grew a Medicinal Chemistry lead optimization program purchased by Big Pharma.

Development of a commercially viable API process (99.11 KB)
Development of a commercially viable, multi-kilogram process suitable for validation with a local client.